KDM1B anticorps (AA 451-544)

N° du produit ABIN7158728

Détail du produit anti-KDM1B anticorps

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Épitope: AA 451-544

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM1B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Lysine-specific histone demethylase 1B protein (451-544AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KDM1B

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Autre désignation: KDM1B (KDM1B Produits)

Synonymes: anticorps AOF1, anticorps C6orf193, anticorps LSD2, anticorps bA204B7.3, anticorps dJ298J15.2, anticorps 4632428N09Rik, anticorps AI482520, anticorps Aof1, anticorps lysine demethylase 1B, anticorps lysine-specific histone demethylase 1B, anticorps lysine (K)-specific demethylase 1B, anticorps KDM1B, anticorps LOC577549, anticorps kdm1b, anticorps Kdm1b

Sujet:

Background: Histone demethylase that demethylates \'Lys-4\' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated \'Lys-4\' of histone H3. Has no effect on tri-methylated \'Lys-4\', mono-, di- or tri-methylated \'Lys-9\', mono-, di- or tri-methylated \'Lys-27\', mono-, di- or tri-methylated \'Lys-36\' of histone H3, or on mono-, di- or tri-methylated \'Lys-20\' of histone H4 (By similarity).

Aliases: amine oxidase (flavin containing) domain 1 antibody, amine oxidase, flavin containing 1 antibody, AOF1 antibody, bA204B7.3 antibody, C6orf193 antibody, dJ298J15.2 antibody, Flavin-containing amine oxidase domain-containing protein 1 antibody, FLJ33898 antibody, FLJ34109 antibody, FLJ43328 antibody, KDM1B antibody, KDM1B_HUMAN antibody, LSD2 antibody, lysine (K)-specific demethylase 1B antibody, Lysine-specific demethylase 2 antibody, Lysine-specific histone demethylase 1B antibody, Lysine-specific histone demethylase 2 antibody

UniProt: Q8NB78

Pathways: L'effet Warburg