MAML1 anticorps (AA 1-45)

N° du produit ABIN7159033

Détail du produit anti-MAML1 anticorps

Antigène: MAML1 (Mastermind-Like 1 (MAML1))

Épitope: AA 1-45

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAML1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Mastermind-like protein 1 protein (1-45AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MAML1

Antigène: MAML1 (Mastermind-Like 1 (MAML1))

Autre désignation: MAML1 (MAML1 Produits)

Synonymes: anticorps mam1, anticorps mam-1, anticorps xmam1, anticorps MAML1, anticorps AI644666, anticorps AW743257, anticorps D930008C07Rik, anticorps Mam-1, anticorps Mam1, anticorps mKIAA0200, anticorps mastermind like transcriptional coactivator 1 L homeolog, anticorps mastermind like transcriptional coactivator 1, anticorps mastermind like 1 (Drosophila), anticorps mastermind-like transcriptional coactivator 1, anticorps maml1.L, anticorps MAML1, anticorps Maml1

Sujet:

Background: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.

Aliases: Mam-1 antibody, Mam1 antibody, MAML 1 antibody, Maml1 antibody, MAML1_HUMAN antibody, Mastermind like 1 antibody, Mastermind-like protein 1 antibody

UniProt: Q92585

Pathways: Signalisation Notch, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development