MED1 anticorps (AA 878-1031)

N° du produit ABIN7159100

Détail du produit anti-MED1 anticorps

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Épitope: AA 878-1031

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Mediator of RNA polymerase II transcription subunit 1 protein (878-1031AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MED1

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Autre désignation: MED1 (MED1 Produits)

Synonymes: anticorps CRSP1, anticorps CRSP200, anticorps DRIP205, anticorps DRIP230, anticorps PBP, anticorps PPARBP, anticorps PPARGBP, anticorps RB18A, anticorps TRAP220, anticorps TRIP2, anticorps CRSP-1, anticorps MED1, anticorps pbp, anticorps nbr1, anticorps crsp1, anticorps rb18a, anticorps trip2, anticorps pparbp, anticorps crsp200, anticorps drip205, anticorps drip230, anticorps ppargbp, anticorps trap220, anticorps CG7162, anticorps Dmel\\CG7162, anticorps Med1, anticorps Med1/SOP3/TRAP220, anticorps Trap220, anticorps dTRAP220, anticorps AI480703, anticorps CRSP210, anticorps Pparbp, anticorps l11Jus15, anticorps RGD1559552, anticorps mediator complex subunit 1, anticorps calcitonin-related polypeptide beta, anticorps Mediator complex subunit 1, anticorps mediator of RNA polymerase II transcription subunit 1, anticorps MED1, anticorps CALCB, anticorps med1, anticorps Med1

Sujet:

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (PubMed:10406464, PubMed:11867769, PubMed:12037571, PubMed:12218053, PubMed:12556447, PubMed:14636573, PubMed:15340084, PubMed:15471764, PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).

Aliases: Activator-recruited cofactor 205 kDa component antibody, ARC205 antibody, CRSP1 antibody, CRSP200 antibody, DRIP205 antibody, DRIP230 antibody, MED1 antibody, MED1_HUMAN antibody, Mediator complex subunit 1 antibody, Mediator of RNA polymerase II transcription subunit 1 antibody, p53 regulatory protein RB18A antibody, PBP antibody, Peroxisome proliferator-activated receptor-binding protein antibody, PPAR binding protein antibody, PPAR-binding protein antibody, PPARBP antibody, PPARGBP antibody, RB18A antibody, Thyroid hormone receptor-associated protein complex 220 kDa component antibody, Thyroid receptor-interacting protein 2 antibody, TR-interacting protein 2 antibody, Trap220 antibody, TRIP-2 antibody, TRIP2 antibody, Vitamin D receptor-interacting protein complex component DRIP205 antibody

UniProt: Q15648

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha