MED12 anticorps (AA 1742-2011)

N° du produit ABIN7159104

Détail du produit anti-MED12 anticorps

Antigène: MED12 (Mediator Complex Subunit 12 (MED12))

Épitope: AA 1742-2011

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED12 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Mediator of RNA polymerase II transcription subunit 12 protein (1742-2011AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MED12

Antigène: MED12 (Mediator Complex Subunit 12 (MED12))

Autre désignation: MED12 (MED12 Produits)

Synonymes: anticorps ARC240, anticorps CAGH45, anticorps FGS1, anticorps HOPA, anticorps MED12S, anticorps OHDOX, anticorps OKS, anticorps OPA1, anticorps TNRC11, anticorps TRAP230, anticorps 230kDa, anticorps Mopa, anticorps OPA-1, anticorps Tnrc11, anticorps Trap230, anticorps mediator complex subunit 12, anticorps MED12, anticorps Med12, anticorps med12

Sujet:

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

Aliases: Activator recruited cofactor 240 kDa component antibody, Activator-recruited cofactor 240 kDa component antibody, ARC240 antibody, CAG repeat protein 45 antibody, CAGH45 antibody, HOPA antibody, KIAA0192 antibody, MED12 antibody, MED12_HUMAN antibody, Mediator complex subunit 12 antibody, Mediator of RNA polymerase II transcription subunit 12 antibody, OPA containing protein antibody, OPA-containing protein antibody, Thyroid hormone receptor associated protein complex 230 kDa component antibody, Thyroid hormone receptor-associated protein complex 230 kDa component antibody, TNRC11 antibody, Trap230 antibody, Trinucleotide repeat containing gene 11 protein antibody, Trinucleotide repeat-containing gene 11 protein antibody

UniProt: Q93074

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation