STEAP1 anticorps (AA 3-69)

N° du produit ABIN7159501

Détail du produit anti-STEAP1 anticorps

Antigène: STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))

Épitope: AA 3-69

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STEAP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Metalloreductase STEAP1 protein (3-69AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur STEAP1

Antigène: STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))

Autre désignation: STEAP1 (STEAP1 Produits)

Sujet:

Background: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis By similarity. Mediates \\\'Lys-63\\\'-linked polyubiquitination of TBK1, which probably participates in kinase activation.

Aliases: 2410007B19Rik antibody, EC 1.16.1.- antibody, Metalloreductase STEAP1 antibody, MGC19484 antibody, PRSS 24 antibody, PRSS24 antibody, Six transmembrane epithelial antigen of prostate antibody, Six transmembrane epithelial antigen of the prostate 1 antibody, Six transmembrane epithelial antigen of the prostate antibody, Six-transmembrane epithelial antigen of prostate 1 antibody, STEA1_HUMAN antibody, STEAP 1 antibody, Steap antibody, STEAP1 antibody

UniProt: Q9UHE8

Pathways: Transition Metal Ion Homeostasis