SMCR7L anticorps (AA 51-309) (Biotin)

N° du produit ABIN7159854

Détail du produit anti-SMCR7L anticorps (Biotin)

Antigène: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Épitope: AA 51-309

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMCR7L est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Mitochondrial dynamics protein MID51 protein (51-309AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SMCR7L

Antigène: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Autre désignation: MIEF1 (SMCR7L Produits)

Synonymes: anticorps MGC115280, anticorps HSU79252, anticorps MID51, anticorps MIEF1, anticorps dJ1104E15.3, anticorps A230016E22, anticorps AI452372, anticorps im:7156228, anticorps smcr7l, anticorps zgc:162279, anticorps mitochondrial elongation factor 1, anticorps mitochondrial elongation factor 1 S homeolog, anticorps MIEF1, anticorps mief1.S, anticorps Mief1, anticorps mief1

Sujet:

Background: Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.

Aliases: MIEF1 antibody, MID51 antibody, SMCR7L antibody, Mitochondrial dynamics protein MID51 antibody, Mitochondrial dynamics protein of 51 kDa antibody, Mitochondrial elongation factor 1 antibody, Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like antibody, SMCR7-like protein antibody

UniProt: Q9NQG6