C20orf72 anticorps (AA 81-260)

N° du produit ABIN7159874

Détail du produit anti-C20orf72 anticorps

Antigène: C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))

Épitope: AA 81-260

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C20orf72 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Mitochondrial genome maintenance exonuclease 1 protein (81-260AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur C20orf72

Antigène: C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))

Autre désignation: MGME1 (MGME1 Produits)

Synonymes: anticorps C20orf72, anticorps DDK1, anticorps MTDPS11, anticorps bA504H3.4, anticorps mitochondrial genome maintenance exonuclease 1, anticorps MGME1

Sujet:

Background: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5\'-3\' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.

Aliases: MGME1 antibody, C20orf72 antibody, DDK1Mitochondrial genome maintenance exonuclease 1 antibody, EC 3.1.-.- antibody

UniProt: Q9BQP7