BUB1B anticorps (AA 230-394)

N° du produit ABIN7160080

Détail du produit anti-BUB1B anticorps

Antigène: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Épitope: AA 230-394

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BUB1B est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Mitotic checkpoint serine/threonine-protein kinase BUB1 beta protein (230-394AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BUB1B

Antigène: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Autre désignation: BUB1B (BUB1B Produits)

Synonymes: anticorps BUB1beta, anticorps BUBR1, anticorps Bub1A, anticorps MAD3L, anticorps MVA1, anticorps SSK1, anticorps hBUBR1, anticorps AU045529, anticorps bub1b, anticorps BUB1, anticorps BUB1-like, anticorps BubR1, anticorps BubRI, anticorps CG14030, anticorps CG14030/Bub1, anticorps Dmel\\CG14030, anticorps bub1, anticorps BUB1 mitotic checkpoint serine/threonine kinase B, anticorps BUB1B, mitotic checkpoint serine/threonine kinase, anticorps BUB1B, mitotic checkpoint serine/threonine kinase L homeolog, anticorps Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, anticorps Bub1 kinase, anticorps BUB1B, anticorps Bub1b, anticorps bub1b.L, anticorps bub1b, anticorps Bub1

Sujet:

Background: Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE. Negatively regulates PLK1 activity in interphase cells and suppresses centrosome amplification. Also implicated in triggering apoptosis in polyploid cells that exit aberrantly from mitotic arrest. May play a role for tumor suppression.

Aliases: Beta homolg of S. cerevisiae BUB 1 antibody, Beta homolg of S. cerevisiae budding uninhibited by benzimidazoles antibody, BUB 1B antibody, BUB1 budding uninhibited by benzimidazoles 1 homolog beta antibody, Bub1A antibody, BUB1B antibody, BUB1B_HUMAN antibody, BUB1beta antibody, BUBR1 antibody, Budding Uninhibited by Benzimidazoles 1 beta antibody, Budding uninhibited by benzimidazoles 1 homolog beta (yeast) antibody, hBUBR1 antibody, MAD3/BUB1 related protein kinase antibody, MAD3/BUB1-related protein kinase antibody, MAD3L antibody, Mitotic checkpoint gene BUB1B antibody, Mitotic checkpoint kinase MAD3L antibody, Mitotic checkpoint serine/threonine protein kinase BUB1 beta antibody, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta antibody, MVA1 antibody, OTTHUMP00000160319 antibody, Protein SSK1 antibody, SSK 1 antibody, SSK1 antibody

UniProt: O60566