MOBKL1A anticorps (AA 2-216)

N° du produit ABIN7160120

Détail du produit anti-MOBKL1A anticorps

Antigène: MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))

Épitope: AA 2-216

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MOBKL1A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human MOB kinase activator 1B protein (2-216AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:500-1:2000, IF:1:200-1:500, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MOBKL1A

Antigène: MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))

Autre désignation: MOB1B (MOB1B Produits)

Synonymes: anticorps MATS2, anticorps MOB4A, anticorps MOBKL1A, anticorps 1110003E08Rik, anticorps AU015450, anticorps B230364F10, anticorps Mobkl1a, anticorps mobkl1a, anticorps mobkl1aa, anticorps wu:fj65h03, anticorps zgc:56156, anticorps zgc:77872, anticorps MOB1B, anticorps mob4a, anticorps mats2, anticorps C2orf6, anticorps MOB1, anticorps MOBK1B, anticorps Mob4B, anticorps cb512, anticorps mobkl1ab, anticorps sb:cb512, anticorps zgc:111840, anticorps MOB kinase activator 1B, anticorps MOB kinase activator 1Ba, anticorps Mps one binder kinase activator-like 1A, anticorps mps one binder kinase activator-like 1A, anticorps MOB kinase activator 1B L homeolog, anticorps MOB kinase activator 1Bb, anticorps MOB1B, anticorps Mob1b, anticorps mob1ba, anticorps mol1a, anticorps LOC100282811, anticorps LOC100285953, anticorps mob1b, anticorps mob1b.L, anticorps mob1bb

Sujet:

Background: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.

Aliases: MATS 2 antibody, MATS2 antibody, MGC33910 antibody, Mob 1A antibody, Mob 1B antibody, MOB 4A antibody, MOB kinase activator 1B antibody, Mob1 homolog 1A antibody, MOB1 Mps One Binder homolog B antibody, MOB1 Mps one binder kinase activator like 1A antibody, Mob1A antibody, Mob1B antibody, MOBKL 1A antibody, MOBKL1A antibody, MOL1A_HUMAN antibody, Mps one binder kinase activator like 1A antibody, Mps one binder kinase activator-like 1A antibody, Protein Mob4A antibody

UniProt: Q7L9L4