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MOBKL1A anticorps (AA 2-216) (FITC)

MOB1B Reactivité: Humain Hôte: Lapin Polyclonal FITC
N° du produit ABIN7160122
  • Antigène Voir toutes MOBKL1A (MOB1B) Anticorps
    MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
    Épitope
    • 8
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 2-216
    Reactivité
    • 41
    • 15
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 36
    • 5
    Lapin
    Clonalité
    • 36
    • 5
    Polyclonal
    Conjugué
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MOBKL1A est conjugé à/à la FITC
    Application
    Veuillez nous consulter SVP
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human MOB kinase activator 1B protein (2-216AA)
    Isotype
    IgG
    Top Product
    Discover our top product MOB1B Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
    Autre désignation
    MOB1B (MOB1B Produits)
    Sujet

    Background: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.

    Aliases: MATS 2 antibody, MATS2 antibody, MGC33910 antibody, Mob 1A antibody, Mob 1B antibody, MOB 4A antibody, MOB kinase activator 1B antibody, Mob1 homolog 1A antibody, MOB1 Mps One Binder homolog B antibody, MOB1 Mps one binder kinase activator like 1A antibody, Mob1A antibody, Mob1B antibody, MOBKL 1A antibody, MOBKL1A antibody, MOL1A_HUMAN antibody, Mps one binder kinase activator like 1A antibody, Mps one binder kinase activator-like 1A antibody, Protein Mob4A antibody

    UniProt
    Q7L9L4
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