SMAD7 anticorps (AA 36-247)

N° du produit ABIN7160246

Détail du produit anti-SMAD7 anticorps

Antigène: SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

Épitope: AA 36-247

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Mothers against decapentaplegic homolog 7 protein (36-247AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IF:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SMAD7

Antigène: SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

Autre désignation: SMAD7 (SMAD7 Produits)

Synonymes: anticorps CRCS3, anticorps MADH7, anticorps MADH8, anticorps Smad7a, anticorps Madh7, anticorps Smad10, anticorps madh7, anticorps xsmad7, anticorps wu:fj60c10, anticorps SMAD family member 7, anticorps SMAD family member 7 L homeolog, anticorps SMAD7, anticorps Smad7, anticorps smad7.L, anticorps smad7

Sujet:

Background: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

Aliases: CRCS3 antibody, FLJ16482 antibody, hSMAD 7 antibody, hSMAD7 antibody, MAD (mothers against decapentaplegic Drosophila) homolog 7 antibody, MAD antibody, Mad homolog 7 antibody, MAD homolog 8 antibody, MAD mothers against decapentaplegic homolog 7 antibody, MADH 7 antibody, MADH 8 antibody, MADH6 antibody, MADH7 antibody, MADH8 antibody, Mothers Against Decapentaplegic Drosophila Homolog of 6 antibody, Mothers Against Decapentaplegic Drosophila Homolog of 7 antibody, Mothers against decapentaplegic homolog 7 antibody, Mothers against decapentaplegic homolog 8 antibody, Mothers against DPP homolog 7 antibody, Mothers against DPP homolog 8 antibody, SMA- AND MAD-RELATED PROTEIN 7 antibody, SMAD 7 antibody, SMAD antibody, SMAD family member 7 antibody, SMAD, mothers against DPP homolog 7 (Drosophila) antibody, SMAD, mothers against DPP homolog 7 antibody, SMAD6 antibody, Smad7 antibody, SMAD7_HUMAN antibody

UniProt: O15105

Pathways: Interferon-gamma Pathway, Cell-Cell Junction Organization