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MYOC anticorps (AA 183-294) (FITC)

MYOC Reactivité: Humain Hôte: Lapin Polyclonal FITC
N° du produit ABIN7160498
  • Antigène Voir toutes MYOC Anticorps
    MYOC (Myocilin (MYOC))
    Épitope
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 183-294
    Reactivité
    • 29
    • 15
    • 15
    • 6
    • 2
    Humain
    Hôte
    • 25
    • 4
    Lapin
    Clonalité
    • 26
    • 3
    Polyclonal
    Conjugué
    • 16
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MYOC est conjugé à/à la FITC
    Application
    Veuillez nous consulter SVP
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Myocilin protein (183-294AA)
    Isotype
    IgG
    Top Product
    Discover our top product MYOC Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    MYOC (Myocilin (MYOC))
    Autre désignation
    MYOC (MYOC Produits)
    Synonymes
    anticorps MYOC, anticorps MGC136645, anticorps zgc:136645, anticorps AI957332, anticorps GLC1A, anticorps TIGR, anticorps GPOA, anticorps JOAG, anticorps JOAG1, anticorps myocilin, anticorps Tigr, anticorps myocilin, anticorps MYOC, anticorps myoc, anticorps Myoc
    Sujet

    Background: Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling. Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling. Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling. Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex. Involved in positive regulation of mitochondrial depolarization. Plays a role in neurite outgrowth. May participate in the obstruction of fluid outflow in the trabecular meshwork.

    Aliases: GLC1A antibody, GPOA antibody, JOAG antibody, JOAG1 antibody, Mutated trabecular meshwork-induced glucocorticoid response protein antibody, MYOC antibody, MYOC_HUMAN antibody, Myocilin antibody, Myocilin, trabecular meshwork inducible glucocorticoid antibody, TIGR antibody, Trabecular meshwork induced glucocorticoid response protein antibody, Trabecular meshwork-induced glucocorticoid response protein antibody

    UniProt
    Q99972
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