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DMPK anticorps (AA 243-424) (HRP)

DMPK Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7160626
  • Antigène Voir toutes DMPK Anticorps
    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
    Épitope
    • 15
    • 8
    • 8
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 243-424
    Reactivité
    • 40
    • 21
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 52
    • 5
    Lapin
    Clonalité
    • 54
    • 3
    Polyclonal
    Conjugué
    • 24
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DMPK est conjugé à/à la HRP
    Application
    • 31
    • 24
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Myotonin-protein kinase protein (243-424AA)
    Isotype
    IgG
    Top Product
    Discover our top product DMPK Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))
    Autre désignation
    DMPK (DMPK Produits)
    Synonymes
    anticorps DMPK, anticorps DM, anticorps DM1, anticorps DM1PK, anticorps DMK, anticorps MDPK, anticorps MT-PK, anticorps Dm15, anticorps DM1 protein kinase, anticorps dystrophia myotonica-protein kinase, anticorps DMPK, anticorps Dmpk
    Sujet

    Background: Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis. Phosphorylates PLN, a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes. May also phosphorylate FXYD1/PLM which is able to induce chloride currents. May also play a role in synaptic plasticity.

    Aliases: DM 1 antibody, DM antibody, DM kinase antibody, DM protein kinase antibody, DM-kinase antibody, DM1 antibody, DM1 protein kinase antibody, DM1PK antibody, DMK antibody, DMPK antibody, DMPK_HUMAN antibody, Dystrophia myotonica 1 antibody, Dystrophia myotonica protein kinase antibody, MDPK antibody, MT PK antibody, MT-PK antibody, Myotonic dystrophy associated protein kinase antibody, Myotonic dystrophy protein kinase antibody, Myotonin protein kinase A antibody, Myotonin protein kinase antibody, Myotonin-protein kinase antibody, Thymopoietin homolog antibody

    UniProt
    Q09013
    Pathways
    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
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