NAT8 anticorps (AA 64-227) (HRP)

N° du produit ABIN7160715

Détail du produit anti-NAT8 anticorps (HRP)

Antigène: NAT8 (N-Acetyltransferase 8 (NAT8))

Épitope: AA 64-227

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAT8 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human N-acetyltransferase 8 protein (64-227AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NAT8

Antigène: NAT8 (N-Acetyltransferase 8 (NAT8))

Autre désignation: NAT8 (NAT8 Produits)

Synonymes: anticorps Cml4, anticorps ATase2, anticorps CML1, anticorps GLA, anticorps Hcml1, anticorps TSC501, anticorps TSC510, anticorps 0610037O16Rik, anticorps N-acetyltransferase 8, anticorps N-acetyltransferase 8 (putative), anticorps N-acetyltransferase 8 (GCN5-related), anticorps Nat8, anticorps NAT8

Sujet:

Background: Acetylates the free alpha-amino group of cysteine S-conjugates to form mercapturic acids (PubMed:20392701). This is the final step in a major route for detoxification of a wide variety of reactive electrophiles which starts with their incorporation into glutathione S-conjugates. The glutathione S-conjugates are then further processed into cysteine S-conjugates and finally mercapturic acids which are water soluble and can be readily excreted in urine or bile. Alternatively, may have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1 (PubMed:24556617). May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (PubMed:19011241).

Aliases: acetyltransferase 2 antibody, ATase2 antibody, Camello, Xenopus, homolog of, 1 antibody, Camello-like protein 1 antibody, CML1 antibody, cysteinyl-conjugate N-acetyltransferase antibody, GLA antibody, Hcml1 antibody, kidney- and liver-specific gene product antibody, N-acetyltransferase 8 (camello like) antibody, N-acetyltransferase 8 (GCN5-related, putative) antibody, N-acetyltransferase 8 antibody, NAT8 antibody, NAT8_HUMAN antibody, Probable N-acetyltransferase 8 antibody, TSC501 antibody, TSC510 antibody

UniProt: Q9UHE5