SMYD2A anticorps (AA 115-272)

N° du produit ABIN7160774

Détail du produit anti-SMYD2A anticorps

Antigène: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Épitope: AA 115-272

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMYD2A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human N-lysine methyltransferase SMYD2 protein (115-272AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SMYD2A

Antigène: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Autre désignation: SMYD2 (SMYD2A Produits)

Synonymes: anticorps HSKM-B, anticorps KMT3C, anticorps ZMYND14, anticorps 1110020E07Rik, anticorps 4930402C15, anticorps Zmynd14, anticorps smyd2-a, anticorps im:7146196, anticorps smyd2, anticorps wu:fc02f02, anticorps zgc:110553, anticorps si:dkey-121j17.3, anticorps zgc:136609, anticorps SET and MYND domain containing 2, anticorps SET and MYND domain containing 2 S homeolog, anticorps SET and MYND domain containing 2a, anticorps SET and MYND domain containing 2b, anticorps SMYD2, anticorps Smyd2, anticorps smyd2.S, anticorps smyd2a, anticorps smyd2b

Sujet:

Background: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 \\\'Lys-4\\\' (H3K4me) and dimethylates histone H3 \\\'Lys-36\\\' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates \\\'Lys-370\\\' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at \\\'Lys-860\\\'.

Aliases: Histone methyltransferase SMYD2 antibody, HSKM B antibody, HSKM-B antibody, HSKMB antibody, KMT3C antibody, Lysine N-methyltransferase 3C antibody, MGC119305 antibody, N lysine methyltransferase SMYD2 antibody, N-lysine methyltransferase SMYD2 antibody, SET and MYND domain containing 2 antibody, SET and MYND domain containing protein 2 antibody, SET and MYND domain-containing protein 2 antibody, Smyd2 antibody, SMYD2_HUMAN antibody, Zinc finger MYND domain containing 14 antibody, ZMYND14 antibody

UniProt: Q9NRG4