PDZK1 anticorps (AA 1-519) (Biotin)

N° du produit ABIN7355137

Détail du produit anti-PDZK1 anticorps (Biotin)

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Épitope: AA 1-519

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDZK1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Na(+)/H(+) exchange regulatory cofactor NHE-RF3 protein (1-519AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PDZK1

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Autre désignation: PDZK1 (PDZK1 Produits)

Synonymes: anticorps xpdzk1, anticorps PDZK1, anticorps CAP70, anticorps CLAMP, anticorps NHERF-3, anticorps NHERF3, anticorps PDZD1, anticorps 1700023D20Rik, anticorps 2610507N21Rik, anticorps 4921513F16Rik, anticorps AI267131, anticorps AI314638, anticorps AL022680, anticorps D3Ertd537e, anticorps Pdzd1, anticorps mPDZK1, anticorps Clamp, anticorps PDZ domain containing 1, anticorps PDZ domain containing 1 L homeolog, anticorps PDZK1, anticorps pdzk1.L, anticorps pdzk1, anticorps Pdzk1

Sujet:

Background: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function

Aliases: 1700023D20Rik antibody, 2610507N21Rik antibody, 4921513F16Rik antibody, AI267131 antibody, AI314638 antibody, AL022680 antibody, C terminal linking and modulating protein antibody, CAP70 antibody, CFTR associated protein of 70 kDa antibody, CFTR associated protein, 70-KD antibody, CFTR-associated protein of 70 kDa antibody, CLAMP antibody, D3Ertd537e antibody, Dietary Pi-regulated RNA-1 antibody, Diphor-1 antibody, mPDZK1 antibody, Na(+)/H(+) exchange regulatory cofactor NHE-RF3 antibody, Na(+)/H(+) exchanger regulatory factor 3 antibody, Na/Pi cotransporter C-terminal-associated protein 1 antibody, Na/Pi cotransporter C-terminal-associated protein antibody, NaPi Cap1 antibody, NaPi-Cap1 antibody, NaPiCap1 antibody, NHERF 3 antibody, NHERF-3 antibody, NHERF3 antibody, NHRF3_HUMAN antibody, OTTHUMP00000015572 antibody, PDZ domain containing 1 antibody, PDZ domain containing protein 1 antibody, PDZ domain-containing protein 1 antibody, PDZD1 antibody, PDZK1 antibody, Sodium hydrogen exchanger regulatory factor 3 antibody, Sodium-hydrogen exchanger regulatory factor 3 antibody

UniProt: Q5T2W1