NANOS2 anticorps (AA 1-138)

N° du produit ABIN7161035

Détail du produit anti-NANOS2 anticorps

Antigène: NANOS2 (Nanos Homolog 2 (NANOS2))

Épitope: AA 1-138

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NANOS2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Nanos homolog 2 protein (1-138AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NANOS2

Antigène: NANOS2 (Nanos Homolog 2 (NANOS2))

Autre désignation: NANOS2 (NANOS2 Produits)

Synonymes: anticorps NOS2, anticorps RGD1562436, anticorps nos2, anticorps nanos C2HC-type zinc finger 2, anticorps nanos homolog 2 (Drosophila), anticorps nanos 2, anticorps nanos2 protein, anticorps NANOS2, anticorps Nanos2, anticorps nanos2

Sujet:

Background: Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial stem cell population. Not essential for the assembly of P-bodies but is required for the maintenance of their normal state.

Aliases: NANO2_HUMAN antibody, Nanos homolog 2 antibody, Nanos homolog 2 Drosophila antibody, NANOS2 antibody, NOS-2 antibody, NOS2 antibody

UniProt: P60321

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance