nectin-3 anticorps (AA 310-549)

N° du produit ABIN7161113

Détail du produit anti-nectin-3 anticorps

Antigène: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Épitope: AA 310-549

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp nectin-3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Nectin-3 protein (310-549AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur nectin-3

Antigène: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Autre désignation: NECTIN3 (NECTIN3 Produits)

Synonymes: anticorps PVRL3, anticorps CD113, anticorps CDW113, anticorps NECTIN-3, anticorps PPR3, anticorps PRR3, anticorps PVRR3, anticorps 2610301B19Rik, anticorps 3000002N23Rik, anticorps 4921513D19Rik, anticorps AA407785, anticorps AU016832, anticorps AW538082, anticorps nectin cell adhesion molecule 3, anticorps poliovirus receptor-related 3, anticorps Nectin3, anticorps NECTIN3, anticorps PVRL3, anticorps nectin3

Sujet:

Background: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.

Aliases: CD113 antibody, CDw113 antibody, DKFZP566B0846 antibody, FLJ90624 antibody, Nectin-3 antibody, Nectin3 antibody, Poliovirus receptor related 3 antibody, Poliovirus receptor related protein 3 antibody, Poliovirus receptor-like 3 antibody, Poliovirus receptor-related protein 3 antibody, PPR3 antibody, PRR3 antibody, Pvrl3 antibody, PVRL3_HUMAN antibody, PVRR3 antibody

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization