C19orf46 anticorps (AA 1-242)

N° du produit ABIN7161174

Détail du produit anti-C19orf46 anticorps

Antigène: C19orf46 (Chromosome 19 Open Reading Frame 46 (C19orf46))

Épitope: AA 1-242

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C19orf46 est non-conjugé

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Nesprin-4 protein (1-242AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur C19orf46

Antigène: C19orf46 (Chromosome 19 Open Reading Frame 46 (C19orf46))

Autre désignation: SYNE4 (C19orf46 Produits)

Synonymes: anticorps C19orf46, anticorps Nesp4, anticorps C18H19orf46, anticorps 0610012K07Rik, anticorps AI428936, anticorps RGD1304580, anticorps C1H19orf46, anticorps spectrin repeat containing nuclear envelope family member 4, anticorps spectrin repeat containing, nuclear envelope family member 4, anticorps SYNE4, anticorps Syne4

Sujet:

Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus.

Aliases: SYNE4 antibody, C19orf46 antibody, Nesprin-4 antibody, KASH domain-containing protein 4 antibody, KASH4 antibody, Nuclear envelope spectrin repeat protein 4 antibody

UniProt: Q8N205