NEUROD2 anticorps (AA 254-339)

N° du produit ABIN7161286

Détail du produit anti-NEUROD2 anticorps

Antigène: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Épitope: AA 254-339

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEUROD2 est non-conjugé

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Neurogenic differentiation factor 2 protein (254-339AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NEUROD2

Antigène: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Autre désignation: NEUROD2 (NEUROD2 Produits)

Synonymes: anticorps NEUROD2, anticorps ndrf, anticorps MGC145932, anticorps Ndrf, anticorps bHLHa1, anticorps ndr2, anticorps wu:fj49a11, anticorps zNdr2, anticorps NDRF, anticorps neuronal differentiation 2, anticorps neurogenic differentiation 2, anticorps NEUROD2, anticorps neurod2, anticorps Neurod2

Sujet:

Background: Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation, prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections, involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity).

Aliases: bHLHa1 antibody, class A basic helix loop helix protein 1 antibody, Class A basic helix-loop-helix protein 1 antibody, NDF2_HUMAN antibody, NDR2 antibody, NDRF antibody, neuroD related factor antibody, NeuroD-related factor antibody, NeuroD2 antibody, neurogenic basic helix loop helix protein antibody, neurogenic differentiation 2 antibody, Neurogenic differentiation factor 2 antibody, neuronal differentiation 2 antibody

UniProt: Q15784