NrCAM anticorps (AA 1194-1299)

N° du produit ABIN7161362

Détail du produit anti-NrCAM anticorps

Antigène: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Épitope: AA 1194-1299

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NrCAM est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Neuronal cell adhesion molecule protein (1194-1299AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NrCAM

Antigène: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Autre désignation: NRCAM (NRCAM Produits)

Synonymes: anticorps CD56, anticorps MSK39, anticorps NCAM, anticorps Bravo, anticorps C030017F07Rik, anticorps C130076O07Rik, anticorps mKIAA0343, anticorps NRCAM, anticorps si:dkey-240a12.1, anticorps Nr-CAM, anticorps neural cell adhesion molecule 1, anticorps neuronal cell adhesion molecule, anticorps neuronal cell adhesion molecule L homeolog, anticorps neuronal cell adhesion molecule a, anticorps NCAM1, anticorps NRCAM, anticorps Nrcam, anticorps nrcam.L, anticorps nrcama, anticorps nrcam

Sujet:

Background: Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes, not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.

Aliases: Bravo antibody, hBravo antibody, Neuronal cell adhesion molecule antibody, Neuronal surface protein Bravo antibody, Ng CAM related antibody, Ng-CAM-related antibody, NgCAM related cell adhesion molecule antibody, NgCAM-related cell adhesion molecule antibody, Nr CAM antibody, Nr-CAM antibody, Nrcam antibody, NRCAM_HUMAN antibody

UniProt: Q92823

Pathways: Regulation of Cell Size