Neuropilin 1 anticorps (AA 684-923)

N° du produit ABIN7161434

Détail du produit anti-Neuropilin 1 anticorps

Antigène: Neuropilin 1 (NRP1)

Épitope: AA 684-923

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuropilin 1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity purified

Immunogène: Recombinant Human Neuropilin-1 protein (684-923AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Neuropilin 1

Antigène: Neuropilin 1 (NRP1)

Autre désignation: NRP1 (NRP1 Produits)

Synonymes: anticorps NRP1, anticorps cd304, anticorps neuropilin, anticorps np-1, anticorps npn-1, anticorps nrp, anticorps nrp-1, anticorps vegf165r, anticorps BDCA4, anticorps CD304, anticorps NP1, anticorps NRP, anticorps VEGF165R, anticorps C530029I03, anticorps NP-1, anticorps NPN-1, anticorps Npn1, anticorps Nrp, anticorps neuropilin 1, anticorps neuropilin 1 L homeolog, anticorps NRP1, anticorps nrp1, anticorps Nrp1, anticorps nrp1.L

Sujet:

Background: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

Aliases: A5 protein antibody, BDCA4 antibody, BLOOD DENDRITIC CELL ANTIGEN 4 antibody, CD304 antibody, Neuropilin-1 antibody, Neuropilin1 antibody, NP1 antibody, NPN1 antibody, NRP 1 antibody, NRP antibody, NRP1 antibody, NRP1_HUMAN antibody, transmembrane receptor antibody, Vascular endothelial cell growth factor 165 receptor antibody, VEGF165R antibody

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals