NOS2 anticorps (AA 17-141)

N° du produit ABIN7161627

Détail du produit anti-NOS2 anticorps

Antigène: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Épitope: AA 17-141

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOS2 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Nitric oxide synthase, inducible protein (17-141AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NOS2

Antigène: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Autre désignation: NOS2 (NOS2 Produits)

Synonymes: anticorps HEP-NOS, anticorps INOS, anticorps NOS, anticorps NOS2A, anticorps NOS-II, anticorps Nos-2, anticorps Nos2a, anticorps i-NOS, anticorps iNOS, anticorps iNos, anticorps NOS2a, anticorps NOS2, anticorps BmNOS2, anticorps Nsl, anticorps nos2, anticorps nitric oxide synthase 2, anticorps nitric oxide synthase 2, inducible, anticorps inducible nitric oxide synthase, anticorps inducible nitric-oxide synthase, anticorps nanos C2HC-type zinc finger 2, anticorps NOS2, anticorps Nos2, anticorps nos2, anticorps LOC396821, anticorps NANOS2

Sujet:

Background: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7531687, PubMed:7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on \'Cys-247\' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed:19688109).

Aliases: HEP-NOS antibody, Hepatocyte NOS antibody, HEPNOS antibody, inducible antibody, Inducible nitric oxide synthase antibody, Inducible NO synthase antibody, Inducible NOS antibody, iNOS antibody, MAC NOS antibody, Macrophage NOS antibody, Nitric oxide synthase 2 inducible antibody, Nitric oxide synthase 2 inducible macrophage antibody, nitric oxide synthase 2A (inducible, hepatocytes) antibody, Nitric oxide synthase antibody, Nitric oxide synthase inducible antibody, nitric oxide synthase, macrophage antibody, NOS 2 antibody, NOS antibody, Nos II antibody, NOS type II antibody, nos2 antibody, NOS2_HUMAN antibody, NOS2A antibody, NOS2A, Inducible, Hepatocyte antibody, Peptidyl-cysteine S-nitrosylase NOS2 antibody

UniProt: P35228

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process