TNIK anticorps (pSer764)
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- Antigène Voir toutes TNIK Anticorps
- TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
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Épitope
- pSer764
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TNIK est non-conjugé
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Phosphorylation site corresponds to Ser735 in mouse
- Réactivité croisée
- Souris, Rat
- Homologie
- Human,Dog,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser764
- Isotype
- IgG
- Top Product
- Discover our top product TNIK Anticorps primaire
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- Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
- Autre désignation
- TNIK (TNIK Produits)
- Synonymes
- anticorps RGD1561817, anticorps TNIK, anticorps 1500031A17Rik, anticorps 4831440I19Rik, anticorps AI451411, anticorps C530008O15Rik, anticorps C630040K21Rik, anticorps fc52d11, anticorps msn, anticorps tnikl, anticorps wu:fc52d11, anticorps zgc:63535, anticorps im:6898857, anticorps zgc:123033, anticorps zgc:152783, anticorps tnik, anticorps TRAF2 and NCK interacting kinase, anticorps TRAF2 and NCK interacting kinase a, anticorps TRAF2 and NCK interacting kinase b, anticorps TRAF2 and NCK interacting kinase S homeolog, anticorps TNIK, anticorps Tnik, anticorps tnika, anticorps tnikb, anticorps tnik.S
- Sujet
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Synonyms: TRAF2 and NCK-interacting protein kinase, TNIK, KIAA0551
Background: Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
- ID gène
- 23043
- UniProt
- Q9UKE5
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