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NPRL2 anticorps (AA 1-220)

NPRL2 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7161635
  • Antigène Voir toutes NPRL2 Anticorps
    NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
    Épitope
    • 15
    • 10
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-220
    Reactivité
    • 53
    • 32
    • 19
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 50
    • 2
    • 1
    Lapin
    Clonalité
    • 53
    Polyclonal
    Conjugué
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NPRL2 est non-conjugé
    Application
    • 44
    • 21
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain, Souris
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Nitrogen permease regulator 2-like protein (1-220AA)
    Isotype
    IgG
    Top Product
    Discover our top product NPRL2 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
    Autre désignation
    NPRL2 (NPRL2 Produits)
    Synonymes
    anticorps 2810446G01Rik, anticorps G21, anticorps NPR2L, anticorps Tusc4, anticorps npr2, anticorps npr2l, anticorps tusc4, anticorps NPR2, anticorps TUSC4, anticorps im:6900399, anticorps zgc:153630, anticorps nitrogen permease regulator-like 2, anticorps NPR2 like, GATOR1 complex subunit S homeolog, anticorps NPR2 like, GATOR1 complex subunit, anticorps NPR2-like, GATOR1 complex subunit, anticorps Nprl2, anticorps nprl2.S, anticorps NPRL2, anticorps nprl2
    Sujet

    Background: Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at \\\'Tyr-9\\\', \\\'Tyr-373\\\' and \\\'Tyr-376\\\' residues. May act as a tumor suppressor. Suppresses cell growth and enhances sensitivity to various anticancer drugs. As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.

    Aliases: 2810446G01Rik antibody, G21 protein antibody, Gene 21 protein antibody, Homologous to yeast nitrogen permease (candidate tumor suppressor) antibody, Homologous to yeast nitrogen permease antibody, Nitrogen permease regulator 2-like protein antibody, Nitrogen permease regulator-like 2 (S. cerevisiae) antibody, NPR 2L antibody, NPR L2 antibody, NPR like 2 antibody, NPR2 antibody, NPR2 like antibody, NPR2-like protein antibody, NPR2L antibody, NPRL 2 antibody, NPRL2 antibody, NPRL2_HUMAN antibody, Tumor suppressor candidate 4 antibody, TUSC 4 antibody, TUSC 4 protein antibody, TUSC4 antibody, TUSC4 protein antibody

    UniProt
    Q8WTW4
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