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NMRAL1 anticorps (AA 1-299)

NMRAL1 Reactivité: Humain ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7161661
  • Antigène Voir toutes NMRAL1 Anticorps
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    Épitope
    • 7
    • 1
    • 1
    • 1
    AA 1-299
    Reactivité
    • 11
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 10
    • 2
    Lapin
    Clonalité
    • 12
    Polyclonal
    Conjugué
    • 8
    • 2
    • 1
    • 1
    Cet anticorp NMRAL1 est non-conjugé
    Application
    • 8
    • 6
    • 2
    ELISA, Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human NmrA-like family domain-containing protein 1 protein (1-299AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: IF:1:200-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    Autre désignation
    NMRAL1 (NMRAL1 Produits)
    Synonymes
    anticorps HSCARG, anticorps SDR48A1, anticorps 1110025F24Rik, anticorps AI256624, anticorps RGD1311451, anticorps NmrA like redox sensor 1, anticorps NmrA-like family domain containing 1, anticorps NMRAL1, anticorps Nmral1
    Sujet

    Background: Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.

    Aliases: FLJ25918 antibody, HSCARG antibody, NmrA like family domain containing 1 antibody, NmrA like family domain containing protein 1 antibody, NmrA-like family domain-containing protein 1 antibody, NMRAL1 antibody, NMRL1_HUMAN antibody, SDR48A1 antibody

    UniProt
    Q9HBL8
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