NMRAL1 anticorps (AA 1-299) (Biotin)

N° du produit ABIN7161662

Détail du produit anti-NMRAL1 anticorps (Biotin)

Antigène: NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))

Épitope: AA 1-299

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMRAL1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human NmrA-like family domain-containing protein 1 protein (1-299AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NMRAL1

Antigène: NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))

Autre désignation: NMRAL1 (NMRAL1 Produits)

Synonymes: anticorps HSCARG, anticorps SDR48A1, anticorps 1110025F24Rik, anticorps AI256624, anticorps RGD1311451, anticorps NmrA like redox sensor 1, anticorps NmrA-like family domain containing 1, anticorps NMRAL1, anticorps Nmral1

Sujet:

Background: Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.

Aliases: FLJ25918 antibody, HSCARG antibody, NmrA like family domain containing 1 antibody, NmrA like family domain containing protein 1 antibody, NmrA-like family domain-containing protein 1 antibody, NMRAL1 antibody, NMRL1_HUMAN antibody, SDR48A1 antibody

UniProt: Q9HBL8