ZC3HC1 anticorps (AA 1-260)
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- Antigène Voir toutes ZC3HC1 Anticorps
- ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
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Épitope
- AA 1-260
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ZC3HC1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Nuclear-interacting partner of ALK protein (1-260AA)
- Isotype
- IgG
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- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
- Autre désignation
- ZC3HC1 (ZC3HC1 Produits)
- Synonymes
- anticorps 1110054L24Rik, anticorps AU018540, anticorps AU019789, anticorps HSPC216, anticorps Nipa, anticorps NIPA, anticorps RGD1561099, anticorps zinc finger, C3HC type 1, anticorps zinc finger C3HC-type containing 1, anticorps zinc finger, C3HC-type containing 1, anticorps Zc3hc1, anticorps ZC3HC1
- Sujet
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Background: Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
Aliases: hNIPA antibody, NIPA_HUMAN antibody, Nuclear interacting partner of ALK antibody, Nuclear interacting partner of anaplastic lymphoma kinase antibody, Nuclear-interacting partner of ALK antibody, Nuclear-interacting partner of anaplastic lymphoma kinase antibody, zc3hc1 antibody, Zinc finger C3HC type containing 1 antibody, Zinc finger C3HC-type protein 1 antibody
- UniProt
- Q86WB0
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