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NUMBL anticorps (AA 447-576) (HRP)

NUMBL Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7162088
  • Antigène Voir toutes NUMBL Anticorps
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    Épitope
    • 15
    • 9
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    AA 447-576
    Reactivité
    • 46
    • 9
    • 9
    • 1
    Humain
    Hôte
    • 44
    • 1
    • 1
    Lapin
    Clonalité
    • 45
    • 1
    Polyclonal
    Conjugué
    • 12
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NUMBL est conjugé à/à la HRP
    Application
    • 32
    • 21
    • 16
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Numb-like protein (447-576AA)
    Isotype
    IgG
    Top Product
    Discover our top product NUMBL Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    Autre désignation
    NUMBL (NUMBL Produits)
    Synonymes
    anticorps nbl, anticorps numb, anticorps cag3a, anticorps ctg3a, anticorps numbr, anticorps numb-r, anticorps tnrc23, anticorps numblike, anticorps CAG3A, anticorps CTG3a, anticorps NBL, anticorps NUMB-R, anticorps NUMBLIKE, anticorps NUMBR, anticorps TNRC23, anticorps NUMB like, endocytic adaptor protein, anticorps numb homolog-like L homeolog, anticorps NUMB-like, endocytic adaptor protein, anticorps numb-like, anticorps NUMBL, anticorps numbl.L, anticorps Numbl
    Sujet

    Background: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the \'Lys-48\'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.

    Aliases: CAG 3A antibody, CAG3A antibody, CTG 3a antibody, CTG3a antibody, NBL antibody, NUMB Drosophilia Homolog Like antibody, Numb homolog (Drosophila) like antibody, Numb homolog like antibody, Numb like protein antibody, NUMB R antibody, Numb-like protein antibody, Numb-R antibody, Numb-related gene antibody, Numb-related protein antibody, NUMBL antibody, NUMBL_HUMAN antibody, NUMBLIKE antibody, NUMBR antibody, TNRC 23 antibody, TNRC23 antibody, Trinucleotide repeat-containing gene 23 antibody

    UniProt
    Q9Y6R0
    Pathways
    Cell-Cell Junction Organization
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