NR1H3 anticorps (AA 1-402)
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- Antigène Voir toutes NR1H3 Anticorps
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
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Épitope
- AA 1-402
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR1H3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain, Souris
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Oxysterols receptor LXR-alpha protein (1-402AA)
- Isotype
- IgG
- Top Product
- Discover our top product NR1H3 Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- Autre désignation
- NR1H3 (NR1H3 Produits)
- Synonymes
- anticorps NR1H3, anticorps LXR-a, anticorps LXRA, anticorps RLD-1, anticorps AU018371, anticorps LXR, anticorps RLD1, anticorps Unr1, anticorps LXRalpha, anticorps LXR-alpha, anticorps im:7141239, anticorps wu:fd59b01, anticorps zgc:113339, anticorps zgc:158542, anticorps nuclear receptor subfamily 1 group H member 3, anticorps nuclear receptor subfamily 1, group H, member 3, anticorps NR1H3, anticorps nr1h3, anticorps Nr1h3
- Sujet
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Background: Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:19481530, PubMed:25661920). Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES (By similarity). LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides (By similarity). Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (PubMed:19481530). Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).
Aliases: Liver X receptor alpha antibody, LXR a antibody, LXRA antibody, NR1H3 antibody, NR1H3_HUMAN antibody, Nuclear receptor subfamily 1 group H member 3 antibody, Oxysterols receptor LXR alpha antibody, Oxysterols receptor LXR-alpha antibody, RLD 1 antibody, RLD1 antibody
- UniProt
- Q13133
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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