SIN3A anticorps (AA 1-123)

N° du produit ABIN7162483

Détail du produit anti-SIN3A anticorps

Antigène: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Épitope: AA 1-123

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIN3A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Paired amphipathic helix protein Sin3a protein (1-123AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SIN3A

Antigène: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Autre désignation: SIN3A (SIN3A Produits)

Synonymes: anticorps AW553200, anticorps Sin3, anticorps mKIAA4126, anticorps mSin3A, anticorps zgc:162128, anticorps SIN3A, anticorps SIN3 transcription regulator family member A, anticorps transcriptional regulator, SIN3A (yeast), anticorps paired amphipathic helix protein Sin3a, anticorps SIN3 transcription regulator family member Aa, anticorps SIN3A, anticorps Sin3a, anticorps LOC100641919, anticorps sin3aa, anticorps LOC100439524

Sujet:

Background: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity).

Aliases: AW553200 antibody, DKFZP434K2235 antibody, FLJ90319 antibody, Histone deacetylase complex subunit Sin 3a antibody, Histone deacetylase complex subunit Sin3a antibody, KIAA0700 antibody, Kiaa4126 antibody, mKIAA4126 antibody, Paired amphipathic helix protein Sin 3a antibody, Paired amphipathic helix protein Sin3a antibody, Sin 3a antibody, SIN3 homolog A antibody, SIN3 homolog A transcription regulator (yeast) antibody, SIN3 homolog A transcription regulator antibody, SIN3 transcription regulator homolog A antibody, Sin3a antibody, SIN3A protein antibody, SIN3A_HUMAN antibody, Transcriptional co repressor Sin 3A antibody, Transcriptional co repressor Sin3A antibody, Transcriptional corepressor Sin3a antibody, Transcriptional regulator SIN3A antibody

UniProt: Q96ST3

Pathways: Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha