PTF1A anticorps (AA 224-325)

N° du produit ABIN7162562

Détail du produit anti-PTF1A anticorps

Antigène: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Épitope: AA 224-325

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTF1A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Pancreas transcription factor 1 subunit alpha protein (224-325AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PTF1A

Antigène: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Autre désignation: PTF1A (PTF1A Produits)

Synonymes: anticorps PTF1A, anticorps PTF1, anticorps si:zc142h2.2, anticorps zgc:112216, anticorps Ptf1a/p48, anticorps XPtf1a, anticorps PTF1-p48, anticorps bHLHa29, anticorps PTF1p48, anticorps pancreas specific transcription factor, 1a, anticorps PTF1A, anticorps ptf1a, anticorps Ptf1a

Sujet:

Background: Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5\\\'-CANNTG-3\\\'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.

Aliases: bHLH transcription factor p48 antibody, bHLHa29 antibody, Class A basic helix-loop-helix protein 29 antibody, Class II bHLH protein PTF1A antibody, Exocrine pancreas specific transcription factor p48 antibody, p48 DNA binding subunit of transcription factor PTF1 antibody, p48 DNA-binding subunit of transcription factor PTF1 antibody, PACA antibody, PAGEN2 antibody, Pancreas specific transcription factor 1a antibody, Pancreas transcription factor 1 subunit alpha antibody, Pancreas-specific transcription factor 1a antibody, PTF 1A antibody, PTF1 p48 antibody, PTF1-p48 antibody, Ptf1a antibody, PTF1A_HUMAN antibody, PTF1P48 antibody

UniProt: Q7RTS3

Pathways: Retinoic Acid Receptor Signaling Pathway