PCID2 anticorps (AA 2-250)

N° du produit ABIN7162710

Détail du produit anti-PCID2 anticorps

Antigène: PCID2 (PCI Domain Containing 2 (PCID2))

Épitope: AA 2-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCID2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human PCI domain-containing protein 2 protein (2-250AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PCID2

Antigène: PCID2 (PCI Domain Containing 2 (PCID2))

Autre désignation: PCID2 (PCID2 Produits)

Synonymes: anticorps F10, anticorps RGD1307041, anticorps A730042J05Rik, anticorps ik:tdsubc_1e10, anticorps im:6909928, anticorps wu:fa11f03, anticorps xx:tdsubc_1e10, anticorps zgc:101845, anticorps PCI domain containing 2, anticorps PCI domain containing 2 S homeolog, anticorps PCID2, anticorps Pcid2, anticorps pcid2.S, anticorps pcid2

Sujet:

Background: Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells.

Aliases: CSN12 like protein antibody, CSN12-like protein antibody, DKFZp686C20226 antibody, F10 antibody, FLJ11305 antibody, FLJ99362 antibody, HT004 antibody, MGC16774 antibody, PCI domain containing 2 antibody, PCI domain containing protein 2 antibody, PCI domain-containing protein 2 antibody, PCID2 antibody, PCID2_HUMAN antibody, RP11 - 98F14.6 antibody

UniProt: Q5JVF3