PHF1 anticorps (AA 151-360)

N° du produit ABIN7163042

Détail du produit anti-PHF1 anticorps

Antigène: PHF1 (PHD Finger Protein 1 (PHF1))

Épitope: AA 151-360

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHF1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human PHD finger protein 10 protein (151-360AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PHF1

Antigène: PHF1 (PHD Finger Protein 1 (PHF1))

Autre désignation: PHF1 (PHF1 Produits)

Synonymes: anticorps pcl1, anticorps xpcl1, anticorps MTF2L2, anticorps PCL1, anticorps PHF2, anticorps TDRD19C, anticorps hPHF1, anticorps AW557215, anticorps D17Ertd455e, anticorps Tctex-3, anticorps Tctex3, anticorps mPcl1, anticorps PHD finger protein 1 L homeolog, anticorps PHD finger protein 1, anticorps phf1.L, anticorps PHF1, anticorps Phf1

Sujet:

Background: Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

Aliases: BAF45a antibody, BRG1-associated factor 45a antibody, FLJ10975 antibody, MGC111009 antibody, PHD finger protein 10 antibody, PHD finger protein 10, isoform a antibody, PHD zinc finger protein XAP135 antibody, Phf10 antibody, PHF10_HUMAN antibody, XAP135 antibody

UniProt: Q8WUB8