Sphingomyelin Synthase 1 anticorps (AA 48-137) (HRP)

N° du produit ABIN7163134

Détail du produit anti-Sphingomyelin Synthase 1 anticorps (HRP)

Antigène: Sphingomyelin Synthase 1 (SGMS1)

Épitope: AA 48-137

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sphingomyelin Synthase 1 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Phosphatidylcholine:ceramide cholinephosphotransferase 1 protein (48-137AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Sphingomyelin Synthase 1

Antigène: Sphingomyelin Synthase 1 (SGMS1)

Autre désignation: SGMS1 (SGMS1 Produits)

Sujet:

Background: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

Aliases: SGMS1 antibody, MOB antibody, SMS1 antibody, TMEM23 antibody, Phosphatidylcholine:ceramide cholinephosphotransferase 1 antibody, EC 2.7.8.27 antibody, Medulla oblongata-derived protein antibody, Protein Mob antibody, Sphingomyelin synthase 1 antibody, Transmembrane protein 23 antibody

UniProt: Q86VZ5

Pathways: Cellular Response to Molecule of Bacterial Origin