Pleiotrophin anticorps (AA 33-168)

N° du produit ABIN7163691

Détail du produit anti-Pleiotrophin anticorps

Antigène: Pleiotrophin (PTN)

Épitope: AA 33-168

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Pleiotrophin est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Pleiotrophin protein (33-168AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Pleiotrophin

Antigène: Pleiotrophin (PTN)

Autre désignation: PTN (PTN Produits)

Synonymes: anticorps zHBNF, anticorps zgc:111787, anticorps harp, anticorps hbnf, anticorps X-PTF, anticorps hbgf8, anticorps negf1, anticorps ptn, anticorps PTN, anticorps HARP, anticorps HBGF8, anticorps HBNF, anticorps NEGF1, anticorps PTN-A, anticorps HB-GAM, anticorps HBBM, anticorps HBGF-8, anticorps OSF-1, anticorps HBBN, anticorps OSF, anticorps Osf-1, anticorps Osf1, anticorps Hbnf, anticorps pleiotrophin, anticorps pleiotrophin L homeolog, anticorps ptn, anticorps PTN, anticorps ptn.L, anticorps Ptn

Sujet:

Background: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299). Down-regulates PTPRZ1 activity (PubMed:16814777).

Aliases: HARP antibody, HB-GAM antibody, HBBM antibody, HBGAM antibody, HBGF-8 antibody, HBGF8 antibody, HBNF antibody, HBNF-1 antibody, HBNF1 antibody, heparin affin regulatory protein antibody, Heparin binding growth associated molecule antibody, Heparin binding growth factor 8 antibody, Heparin binding neurite outgrowth promoting factor 1 antibody, Heparin-binding brain mitogen antibody, Heparin-binding growth factor 8 antibody, Heparin-binding growth-associated molecule antibody, heparin-binding neurite outgrowth promoting factor antibody, Heparin-binding neurite outgrowth-promoting factor 1 antibody, NEGF1 antibody, Neurite growth promoting factor 1 antibody, Neurite outgrowth-promoting factor, heparin-binding antibody, OSF-1 antibody, OSF1 antibody, Osteoblast-specific factor 1 antibody, pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) antibody, Pleiotrophin antibody, PTN antibody, PTN_HUMAN antibody

UniProt: P21246

Pathways: Signalisation RTK