PARP3 anticorps (AA 1-240)

N° du produit ABIN7163751

Détail du produit anti-PARP3 anticorps

Antigène: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Épitope: AA 1-240

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Poly [ADP-ribose] polymerase 3 protein (1-240AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PARP3

Antigène: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Autre désignation: PARP3 (PARP3 Produits)

Synonymes: anticorps ADPRT-3, anticorps PARP-3, anticorps PM38, anticorps Adprtl3, anticorps fj17c06, anticorps wu:fj17c06, anticorps zgc:66157, anticorps PARP3, anticorps parp3, anticorps ADPRT3, anticorps ADPRTL2, anticorps ADPRTL3, anticorps ARTD3, anticorps IRT1, anticorps PADPRT-3, anticorps A930002C11Rik, anticorps AW990611, anticorps Adprt3, anticorps pADPRT-3, anticorps seed maturation protein PM38, anticorps poly (ADP-ribose) polymerase family, member 3, anticorps poly(ADP-ribose) polymerase family member 3, anticorps poly(ADP-ribose) polymerase family member 3 L homeolog, anticorps PARP3, anticorps parp3, anticorps parp3.L, anticorps Parp3

Sujet:

Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

Aliases: ADP ribosyltransferase (NAD+, poly (ADP ribose) antibody, ADP ribosyltransferase diphtheria toxin like 3 antibody, ADPRT-3 antibody, ADPRT3 antibody, ADPRTL2 antibody, ADPRTL3 antibody, ARTD3 antibody, hPARP 3 antibody, hPARP-3 antibody, hPARP3 antibody, IRT 1 antibody, IRT1 antibody, NAD(+) ADP ribosyltransferase 3 antibody, NAD(+) ADP-ribosyltransferase 3 antibody, NAD+ ADP ribosyltransferase 3 antibody, pADPRT 3 antibody, pADPRT-3 antibody, pADPRT3 antibody, PARP 3 antibody, PARP-3 antibody, PARP3 antibody, PARP3_HUMAN antibody, Poly (ADP ribose) polymerase family, member 3 antibody, Poly (ADP ribose) synthetase 3 antibody, Poly [ADP-ribose] polymerase 3 antibody, Poly[ADP ribose] synthetase 3 antibody, Poly[ADP-ribose] synthase 3 antibody

UniProt: Q9Y6F1