PCGF2 anticorps (AA 103-316) (FITC)
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- Antigène Voir toutes PCGF2 Anticorps
- PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
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Épitope
- AA 103-316
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PCGF2 est conjugé à/à la FITC
- Application
- Veuillez nous consulter SVP
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Polycomb group RING finger protein 2 protein (103-316AA)
- Isotype
- IgG
- Top Product
- Discover our top product PCGF2 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
- Autre désignation
- PCGF2 (PCGF2 Produits)
- Synonymes
- anticorps ZNF144, anticorps PCGF2, anticorps MEL-18, anticorps RNF110, anticorps Mel18, anticorps Rnf110, anticorps Zfp144, anticorps mel-18, anticorps polycomb group ring finger 2, anticorps PCGF2, anticorps Pcgf2
- Sujet
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Background: Transcriptional repressor. Binds specifically to the DNA sequence 5\'-GACTNGACT-3\'. Has tumor suppressor activity. May play a role in control of cell proliferation and/or neural cell development. Regulates proliferation of early T progenitor cells by maintaining expression of HES1. Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \'Lys-119\', rendering chromatin heritably changed in its expressibility. Is not functionally redundant with BMI1, unlike BMI1 does not stimulate the E3 ubiquitin-protein ligase activity in a reconstituted PRC1-like complex (By similarity).
Aliases: DNA binding protein Mel 18 antibody, DNA-binding protein Mel-18 antibody, Mel 18 antibody, MGC10545 antibody, PCGF 2 antibody, PCGF2 antibody, PCGF2_HUMAN antibody, Polycomb group ring finger 2 antibody, Polycomb group RING finger protein 2 antibody, RING finger protein 110 antibody, RNF110 antibody, Zinc finger protein 144 antibody, ZNF 144 antibody, ZNF144 antibody
- UniProt
- P35227
- Pathways
- Chromatin Binding
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