PQBP1 anticorps (AA 2-265)

N° du produit ABIN7163840

Détail du produit anti-PQBP1 anticorps

Antigène: PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Épitope: AA 2-265

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PQBP1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Polyglutamine-binding protein 1 protein (2-265AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PQBP1

Antigène: PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Autre désignation: PQBP1 (PQBP1 Produits)

Synonymes: anticorps PQBP1, anticorps MRX55, anticorps MRXS3, anticorps MRXS8, anticorps NPW38, anticorps RENS1, anticorps SHS, anticorps PQBP-1, anticorps Sfc2, anticorps npw38, anticorps polyglutamine binding protein 1, anticorps PQBP1, anticorps Pqbp1

Sujet:

Background: Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species (PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.

Aliases: 38 kDa nuclear protein containing a WW domain antibody, Mental retardation, X linked 55 antibody, MRX55 antibody, MRXS3 antibody, MRXS8 antibody, Npw38 antibody, Nuclear protein containing WW domain 38 kD antibody, OTTHUMP00000025808 antibody, Polyglutamine binding protein 1 antibody, Polyglutamine tract binding protein 1 antibody, Polyglutamine tract-binding protein 1 antibody, Polyglutamine-binding protein 1 antibody, PQBP 1 antibody, PQBP-1 antibody, PQBP1 antibody, PQBP1_HUMAN antibody, RENS1 antibody, SHS antibody, Sutherland Haan X linked mental retardation syndrome antibody

UniProt: O60828

Pathways: Ribonucleoprotein Complex Subunit Organization