KCNC3 anticorps (AA 638-745) (Biotin)
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- Antigène Voir toutes KCNC3 Anticorps
- KCNC3 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3))
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Épitope
- AA 638-745
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KCNC3 est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Potassium voltage-gated channel subfamily C member 3 protein (638-745AA)
- Isotype
- IgG
- Top Product
- Discover our top product KCNC3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- KCNC3 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3))
- Autre désignation
- KCNC3 (KCNC3 Produits)
- Synonymes
- anticorps kcnc3-A, anticorps Kv3.1, anticorps KShIIID, anticorps Kcr2-3, anticorps Kv3.3, anticorps KSHIIID, anticorps KV3.3, anticorps SCA13, anticorps kcnc1, anticorps kshiiid, anticorps kv3.3, anticorps sca13, anticorps potassium voltage-gated channel subfamily C member 3, anticorps potassium channel, voltage gated Shaw related subfamily C, member 1 S homeolog, anticorps potassium voltage gated channel, Shaw-related subfamily, member 3, anticorps potassium channel, voltage gated Shaw related subfamily C, member 3 L homeolog, anticorps potassium voltage-gated channel, Shaw-related subfamily, member 3, anticorps KCNC3, anticorps kcnc1.S, anticorps Kcnc3, anticorps kcnc3.L
- Sujet
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Background: Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient. The channel displays rapid activation and inactivation kinetics (PubMed:10712820, PubMed:26997484, PubMed:22289912, PubMed:23734863, PubMed:16501573, PubMed:19953606, PubMed:21479265, PubMed:25756792). It plays a role in the regulation of the frequency, shape and duration of action potentials in Purkinje cells. Required for normal survival of cerebellar neurons, probably via its role in regulating the duration and frequency of action potentials that in turn regulate the activity of voltage-gated Ca(2+) channels and cellular Ca(2+) homeostasis (By similarity). Required for normal motor function (PubMed:23734863, PubMed:16501573, PubMed:19953606, PubMed:21479265, PubMed:25756792). Plays a role in the reorganization of the cortical actin cytoskeleton and the formation of actin veil structures in neuronal growth cones via its interaction with HAX1 and the Arp2/3 complex (PubMed:26997484).
Aliases: Kcnc3 antibody, KCNC3_HUMAN antibody, KSHIIID antibody, KV3.3 antibody, Potassium voltage gated channel Shaw related subfamily member 3 antibody, Potassium voltage gated channel subfamily C member 3 antibody, Potassium voltage-gated channel subfamily C member 3 antibody, SCA13 antibody, Shaw related subfamily, member 3 antibody, Shaw related voltage gated potassium channel protein 3 antibody, Spinocerebellar ataxia 13 antibody, Voltage gated potassium channel protein KV3.3 antibody, Voltage gated potassium channel subunit Kv3.3 antibody, Voltage-gated potassium channel subunit Kv3.3 antibody
- UniProt
- Q14003
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