PBX1 anticorps (AA 315-430) (HRP)

N° du produit ABIN7164140

Détail du produit anti-PBX1 anticorps (HRP)

Antigène: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Épitope: AA 315-430

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PBX1 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Pre-B-cell leukemia transcription factor 1 protein (315-430AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PBX1

Antigène: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Autre désignation: PBX1 (PBX1 Produits)

Synonymes: anticorps fi29e01, anticorps pbx1b, anticorps wu:fi29e01, anticorps zgc:55265, anticorps 2310056B04Rik, anticorps AI848790, anticorps AU015730, anticorps D230003C07Rik, anticorps Pbx-1, anticorps Pbx1a, anticorps Pbx1b, anticorps PBX1A, anticorps Xpbx1, anticorps Xpbx1b, anticorps PBX homeobox 1, anticorps pre-B-cell leukemia homeobox 1a, anticorps pre B cell leukemia homeobox 1, anticorps pre-B-cell leukemia homeobox 1 S homeolog, anticorps PBX1, anticorps pbx1a, anticorps Pbx1, anticorps pbx1.S

Sujet:

Background: Binds the sequence 5\'-ATCAATCAA-3\'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1,19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with NKX2-5, it is required for spleen development through a mechanism that involves CDKN2B repression (By similarity).

Aliases: DKFZp686B09108 antibody, Homeo box protein PBX1 antibody, Homeo box protein PRL antibody, Homeobox protein PBX 1 antibody, Homeobox protein PBX1 antibody, Homeobox protein PRL antibody, MGC126627 antibody, PBX 1 antibody, Pbx1 antibody, PBX1_HUMAN antibody, Pre B cell leukemia homeobox 1 antibody, Pre B cell leukemia transcription factor 1 antibody, Pre-B-cell leukemia transcription factor 1 antibody, PRL antibody

UniProt: P40424