PSME3 anticorps (AA 2-252)

N° du produit ABIN7164919

Détail du produit anti-PSME3 anticorps

Antigène: PSME3

Épitope: AA 2-252

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSME3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Proteasome activator complex subunit 3 protein (2-252AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PSME3

Antigène: PSME3

Autre désignation: PSME3 (PSME3 Produits)

Synonymes: anticorps AA410043, anticorps AU020960, anticorps Ki, anticorps PA28gamma, anticorps REGgamma, anticorps pa28g, anticorps Ab2-371, anticorps PA28-gamma, anticorps PA28G, anticorps REG-GAMMA, anticorps psme3b, anticorps proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki), anticorps proteasome activator subunit 3, anticorps proteasome activator subunit 3 S homeolog, anticorps Psme3, anticorps PSME3, anticorps psme3.S

Sujet:

Background: Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.

Aliases: 11S regulator complex gamma subunit antibody, 11S regulator complex subunit gamma antibody, Activator of multicatalytic protease subunit 3 antibody, Ki antibody, Ki antigen antibody, Ki nuclear autoantigen antibody, Ki, PA28 gamma antibody, PA28 gamma antibody, PA28g antibody, PA28gamma antibody, Proteasome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) antibody, Proteasome (prosome, macropain) activator subunit 3 antibody, Proteasome activator 28 gamma antibody, Proteasome activator 28 subunit gamma antibody, Proteasome activator complex subunit 3 antibody, Proteasome activator subunit 3 antibody, PSME3 antibody, PSME3_HUMAN antibody, REG GAMMA antibody, REG-gamma antibody

UniProt: P61289

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA