PSMA7 anticorps (AA 5-232)

N° du produit ABIN7164964

Détail du produit anti-PSMA7 anticorps

Antigène: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Épitope: AA 5-232

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMA7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Proteasome subunit alpha type-7 protein (5-232AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PSMA7

Antigène: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Autre désignation: PSMA7 (PSMA7 Produits)

Synonymes: anticorps C6, anticorps HSPC, anticorps RC6-1, anticorps XAPC7, anticorps C6-I, anticorps DDBDRAFT_0185059, anticorps DDBDRAFT_0217080, anticorps DDB_0185059, anticorps DDB_0217080, anticorps hspc, anticorps rc6-1, anticorps xapc7, anticorps psma7, anticorps psma4-B, anticorps proteasome subunit alpha 7, anticorps proteasome (prosome, macropain) subunit, alpha type 7, anticorps 20S proteasome subunit alpha-7, anticorps proteasome subunit alpha 7 S homeolog, anticorps proteasome subunit alpha 7 L homeolog, anticorps PSMA7, anticorps Psma7, anticorps psmA7, anticorps psma7, anticorps psma7.S, anticorps psma7.L

Sujet:

Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response

Aliases: C6 antibody, HSPC antibody, MGC3755 antibody, OTTHUMP00000031449 antibody, OTTHUMP00000031450 antibody, OTTHUMP00000031453 antibody, Proteasome (prosome macropain) subunit alpha type 7 antibody, Proteasome alpha 7 subunit antibody, Proteasome subunit alpha 4 antibody, Proteasome subunit alpha type 7 antibody, Proteasome subunit alpha type-7 antibody, Proteasome subunit RC6 1 antibody, Proteasome subunit RC6-1 antibody, Proteasome subunit XAPC7 antibody, PSA7_HUMAN antibody, PSMA 7 antibody, PSMA7 antibody, RC6 1 antibody, XAPC7 antibody

UniProt: O14818

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA