PRMT7 anticorps (AA 285-390)
-
- Antigène Voir toutes PRMT7 Anticorps
- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
-
Épitope
- AA 285-390
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PRMT7 est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain, Souris
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Protein arginine N-methyltransferase 7 protein (285-390AA)
- Isotype
- IgG
-
-
- Indications d'application
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Antigène
- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
- Autre désignation
- PRMT7 (PRMT7 Produits)
- Sujet
-
Background: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 \\\'Arg-3\\\' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.
Aliases: [Myelin basic protein]-arginine N-methyltransferase PRMT7 antibody, ANM7_HUMAN antibody, FLJ10640 antibody, Histone-arginine N-methyltransferase PRMT7 antibody, KIAA1933 antibody, Myelin basic protein arginine N methyltransferase antibody, OTTHUMP00000174863 antibody, PRMT7 antibody, Protein arginine methyltransferase 7 antibody, Protein arginine N-methyltransferase 7 antibody
- UniProt
- Q9NVM4
- Pathways
- Ribonucleoprotein Complex Subunit Organization
-