EIF2C3 anticorps (AA 251-400)

N° du produit ABIN7165095

Détail du produit anti-EIF2C3 anticorps

Antigène: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Épitope: AA 251-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2C3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Protein argonaute-3 protein (251-400aa)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:100-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EIF2C3

Antigène: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Autre désignation: AGO3 (EIF2C3 Produits)

Synonymes: anticorps EIF2C3, anticorps Eif2c3, anticorps Argonaute3, anticorps ago3, anticorps eif2c3, anticorps eif2c3b, anticorps si:dkey-3n22.3, anticorps AW048688, anticorps C130014L07Rik, anticorps ARGONAUTE 3, anticorps T19E23.8, anticorps T19E23_8, anticorps argonaute 3, RISC catalytic component, anticorps argonaute RISC catalytic component 3b, anticorps argonaute RISC catalytic subunit 3, anticorps argonaute RISC catalytic component 3, anticorps ARGONAUTE 3, anticorps AGO3, anticorps Ago3, anticorps ago3b

Sujet:

Background: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.

Aliases: Protein argonaute-3 (Argonaute3) (hAgo3) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3), AGO3, EIF2C3

UniProt: Q9H9G7

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway