BICD2 anticorps (AA 511-625)

N° du produit ABIN7165140

Détail du produit anti-BICD2 anticorps

Antigène: BICD2 (Bicaudal D Homolog 2 (BICD2))

Épitope: AA 511-625

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BICD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Protein bicaudal D homolog 2 protein (511-625AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BICD2

Antigène: BICD2 (Bicaudal D Homolog 2 (BICD2))

Autre désignation: BICD2 (BICD2 Produits)

Synonymes: anticorps SMALED2, anticorps bA526D8.1, anticorps 0610027D24Rik, anticorps 1110005D12Rik, anticorps AA408834, anticorps mKIAA0699, anticorps MGC84972, anticorps BICD2, anticorps bicd2, anticorps BICD cargo adaptor 2, anticorps bicaudal D homolog 2 (Drosophila), anticorps BICD cargo adaptor 2 L homeolog, anticorps zgc:171572, anticorps BICD2, anticorps Bicd2, anticorps bicd2.L, anticorps bicd2, anticorps zgc:171572

Sujet:

Background: Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623). Contributes to nuclear and centrosomal positioning prior to mitotic entry through regulation of both dynein and kinesin-1. During G2 phase of the cell cycle, associates with RANBP2 at the nuclear pores and recruits dynein and dynactin to the nuclear envelope to ensure proper positioning of the nucleus relative to centrosomes prior to the onset of mitosis (By similarity).

Aliases: bA526D8.1 antibody, Bic D 2 antibody, Bic-D 2 antibody, Bicaudal D homolog 2 (Drosophila) antibody, Bicaudal D homolog 2 antibody, Bicd2 antibody, BICD2_HUMAN antibody, Coiled coil protein BICD2 antibody, Cytoskeleton like bicaudal D protein homolog 2 antibody, Homolog of Drosophila bicaudal D antibody, KIAA0699 antibody, Protein bicaudal D homolog 2 antibody

UniProt: Q8TD16

Pathways: Maintenance of Protein Location