HOOK3 anticorps (AA 357-455)

N° du produit ABIN7165641

Détail du produit anti-HOOK3 anticorps

Antigène: HOOK3 (Hook Homolog 3 (HOOK3))

Épitope: AA 357-455

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOOK3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Protein Hook homolog 3 protein (357-455AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HOOK3

Antigène: HOOK3 (Hook Homolog 3 (HOOK3))

Autre désignation: HOOK3 (HOOK3 Produits)

Synonymes: anticorps 5830454D03Rik, anticorps AI317159, anticorps E330005F07Rik, anticorps HK3, anticorps hook3, anticorps hook microtubule-tethering protein 3, anticorps hook microtubule tethering protein 3, anticorps hook microtubule-tethering protein 3 L homeolog, anticorps Hook3, anticorps HOOK3, anticorps hook3.L

Sujet:

Background: Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).

Aliases: FLJ31058 antibody, h-hook3 antibody, hHK3 antibody, HK3 antibody, hook3 antibody, HOOK3_HUMAN antibody, OTTHUMP00000229200 antibody, Protein Hook homolog 3 antibody

UniProt: Q86VS8

Pathways: Stem Cell Maintenance, Maintenance of Protein Location