INTU anticorps (AA 6-139)

N° du produit ABIN7165653

Détail du produit anti-INTU anticorps

Antigène: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Épitope: AA 6-139

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INTU est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Protein inturned protein (6-139AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur INTU

Antigène: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Autre désignation: INTU (INTU Produits)

Synonymes: anticorps 9230116I04Rik, anticorps 9430087H23Rik, anticorps Pdzd6, anticorps Pdzk6, anticorps mKIAA1284, anticorps INT, anticorps PDZD6, anticorps PDZK6, anticorps Xint, anticorps in, anticorps int, anticorps pdzd6, anticorps inturned planar cell polarity protein, anticorps inturned planar cell polarity protein S homeolog, anticorps Intu, anticorps INTU, anticorps intu, anticorps intu.S

Sujet:

Background: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).

Aliases: Homolog of inturned (X. tropicalis) antibody, INT antibody, intu antibody, Inturned planar cell polarity effector homolog antibody, KIAA1284 antibody, PDZ domain containing 6 antibody, PDZ domain-containing protein 6 antibody, PDZD 6 antibody, PDZD6_HUMAN antibody, PDZK6 antibody

UniProt: Q9ULD6