LIN7A anticorps (AA 1-233)

N° du produit ABIN7346710

Détail du produit anti-LIN7A anticorps

Antigène: LIN7A (Lin-7 Homolog A (LIN7A))

Épitope: AA 1-233

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN7A est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Protein lin-7 homolog A protein (1-233AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LIN7A

Antigène: LIN7A (Lin-7 Homolog A (LIN7A))

Autre désignation: LIN7A (LIN7A Produits)

Synonymes: anticorps LIN-7A, anticorps LIN7, anticorps MALS-1, anticorps TIP-33, anticorps VELI1, anticorps lin7b, anticorps zgc:73090, anticorps AI848705, anticorps Veli, anticorps Veli1, anticorps lin-7 homolog A, crumbs cell polarity complex component, anticorps lin-7 homolog A (C. elegans), anticorps LIN7A, anticorps lin7a, anticorps Lin7a

Sujet:

Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Aliases: hLin-7 antibody, Lin 7 homolog A (C. elegans) antibody, LIN 7A antibody, Lin-7A antibody, LIN7 antibody, LIN7A antibody, LIN7A_HUMAN antibody, MALS-1 antibody, Mammalian LIN 7 1 antibody, Mammalian lin-seven protein 1 antibody, Protein lin-7 homolog A antibody, Tax interaction protein 33 antibody, TIP-33 antibody, Veli-1 antibody, VELI1 antibody, Vertebrate lin-7 homolog 1 antibody, Vertebrate LIN7 homolog 1 antibody

UniProt: O14910

Pathways: Synaptic Membrane