NTAN1 anticorps (AA 219-310) (HRP)

N° du produit ABIN7165840

Détail du produit anti-NTAN1 anticorps (HRP)

Antigène: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Épitope: AA 219-310

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NTAN1 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Protein N-terminal asparagine amidohydrolase protein (219-310AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NTAN1

Antigène: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Autre désignation: NTAN1 (NTAN1 Produits)

Synonymes: anticorps PNAA, anticorps PNAD, anticorps N-terminal Asn amidase, anticorps N-terminal asparagine amidase, anticorps Ntan1, anticorps NTAN1

Sujet:

Background: Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position, nor on acetylated N-terminal peptidyl Asn.

Aliases: NTAN1 antibody, Protein N-terminal asparagine amidohydrolase antibody, EC 3.5.1.121 antibody, Protein NH2-terminal asparagine amidohydrolase antibody, PNAA antibody, Protein NH2-terminal asparagine deamidase antibody, PNAD antibody, Protein N-terminal Asn amidase antibody, Protein N-terminal asparagine amidase antibody, Protein NTN-amidase antibody

UniProt: Q96AB6